CBD is a cannabinoid, a type of substance found naturally in cannabis (marijuana and hemp) plants. CBD does not produce the “high” sensation that many people associate with cannabis. Tetrahydrocannabinol (THC), a distinct form of cannabinoid, is responsible for this sensation.
To control their symptoms, some persons with chronic pain utilize topical CBD products, particularly CBD oil. CBD oil may help you to:
Pain, inflammation, and general discomfort are all symptoms of a range of medical problems.
CBD products and pain treatment have been the subject of promising studies.
CBD may be a viable option for patients who suffer from chronic pain and rely on drugs like opioids, which may be addictive and have several adverse effects. More study is needed, however, to confirm CBD oil’s and other products’ pain-relieving properties.
Epidiolex, an epileptic medicine, is the only CBD product on the market that has been approved by the Food and Drug Administration (FDA).
There are no nonprescription CBD products that have been authorized by the FDA. They aren’t subject to the same purity and dose restrictions as other drugs.
Continue reading to discover more about CBD’s possible pain-relieving properties. You can also discuss it with your doctor to determine whether it’s a viable choice for you.
The endocannabinoid system is a cell-signaling system found in everyone (ECS).
CBD, according to some studies, interacts with endocannabinoid receptors in the brain and immune system, which are a key component of the ECS.
Receptors are little proteins found on the surface of your cells. They receive chemical messages from various stimuli and assist your cells in responding.
This reaction has anti-inflammatory and pain-relieving properties, which aid in pain management. This suggests that CBD oil and other CBD-based treatments may help those who suffer from chronic pain, such as chronic back pain.
A 2018 study looked at how effective CBD is in treating chronic pain. The assessment looked at trials that took place between 1975 and March of this year. Various forms of pain were investigated in this research, including:
Researchers determined that CBD was beneficial in overall pain treatment and had no harmful side effects based on these investigations.
According to a 2016 research involving the usage of CBD in rats with arthritis:
CBD gel was administered to rats for four days in a row. Each day, the rats were given 0.6, 3.1, 6.2, or 62.3 milligrams (mg). The rats’ damaged joints showed less inflammation and discomfort, according to the researchers. There were no noticeable negative consequences.
The pain ratings of rats given modest dosages of 0.6 or 3.1 mg did not improve. The researchers discovered that 6.2 mg/day was an effective level for reducing discomfort and edema in rats.
Furthermore, animals receiving 62.3 mg/day showed similar results to rats receiving 6.2 mg/day. They did not experience reduced discomfort after receiving a significantly higher amount.
CBD gel’s anti-inflammatory and pain-relieving properties might aid those with arthritis. More human research, on the other hand, is required.
There are few studies on CBD and migraines. CBD is also studied when it is combined with THC, rather than when it is used alone, according to the present research.
According to the findings of a 2017 study, CBD and THC can help migraine sufferers experience less acute and severe pain.
Some participants in this two-phase trial were given a mixture of two drugs. One of the compounds has 9% CBD and practically negligible THC. THC was present in the other molecule at a concentration of 19%. Oral dosing was used.
When the dosages were less than 100 mg, there was no effect on pain in phase I. Acute discomfort was reduced by 55% when the dosages were raised to 200 mg.
In phase II, individuals who received a mixture of CBD and THC chemicals saw a 40.4 percent reduction in migraine episodes. The dosage was 200 milligrams per day.
The combination of chemicals was somewhat more effective than 25 mg of tricyclic antidepressant amitriptyline. In the trial, amitriptyline reduced migraine episodes by 40.1 percent.
Cluster headaches were also relieved by the combination of CBD and THC chemicals, but only if the participants had a history of migraines as a kid.
CBD is also used by certain cancer patients. CBD has been demonstrated in studies on mice to help reduce malignant tumors. The majority of human research, on the other hand, has looked at the effect of CBD in controlling pain associated with cancer and cancer therapy.
CBD has been suggested by the National Cancer Institute (NCI) as a feasible solution for minimizing chemotherapy adverse effects such as:
Research participants received oral sprays of a THC-CBD compound in a 2010 study on cancer-related pain. Opioids were utilized in combination with the THC-CBD extract. The extract offered more effective pain alleviation than the opioids alone, according to one study.
A similar conclusion was reported in a 2013 research on THC and THC-CBD oral sprays. Many of the same researchers that worked on the 2010 study contributed to this one. More proof is still required.
CBD has no known side effects, and most topical CBD products do not reach the bloodstream.
However, there are some probable negative effects, such as:
CBD may interact with the following substances:
If any of your drugs or supplements have a “grapefruit warning,” proceed with care. Both grapefruit and CBD interact with enzymes involved in drug metabolism.
CBD, like other medications and supplements, has the potential to cause liver damage.
CBD-rich cannabis extract raised the risk of liver damage in mice, according to one research. Some of the mice, on the other hand, had been force-fed extremely huge doses of CBD-rich cannabis extract.
While there isn’t enough evidence to support CBD or CBD oil as a preferred way of pain relief, researchers believe that these products have a lot of promise.
CBD products may be able to provide comfort for many people suffering from chronic pain without creating intoxication or addiction.
Consult your doctor if you’re interested in trying CBD for chronic pain. They can assist you in determining an appropriate starting dose.
CBD edibles, which include anything from tinctures and oils to candy, cake pops, and chocolates, provide a longer-lasting option to CBD products that are inhaled.